» ОПРЕДЕЛЕНИЕ ИНТЕРФЕРОНА-ГАММА В ТЕСТ-СИСТЕМАХ IGRA – ЗНАЧЕНИЕ В ДИАГНОСТИКЕ ТУБЕРКУЛЕЗА, В ТОМ ЧИСЛЕ У ИММУНОКОМПРОМЕТИРОВАННЫХ ЛИЦ

Аннотация

ОПРЕДЕЛЕНИЕ ИНТЕРФЕРОНА-ГАММА В ТЕСТ-СИСТЕМАХ IGRA – ЗНАЧЕНИЕ В ДИАГНОСТИКЕ ТУБЕРКУЛЕЗА, В ТОМ
ЧИСЛЕ У ИММУНОКОМПРОМЕТИРОВАННЫХ ЛИЦ

Об авторах

Литвинов Виталий Ильич – научный руководитель ГБУЗ «Московский городской научно-практический центр борьбы
с туберкулезом Департамента здравоохранения города Москвы», доктор медицинских наук, профессор, академик РАН
Адрес: 107014, г. Москва, ул. Стромынка, д. 10
Тел. + 7 (495) 268-04-15
e-mail: mnpcbtlv@yandex.ru

Ванеева Татьяна Валерьевна – ведущий научный сотрудник отдела проблем лабораторной диагностики туберкулеза и
патоморфологии ГБУЗ «Московский научно-практический центр борьбы с туберкулезом Департамента здравоохранения
города Москвы», кандидат медицинских наук
Адрес: 107014, Москва, ул. Стромынка, д. 10
Тел. + 7 (495) 603-30-33, тел./факс + 7 (499) 785-20-82

Куликовская Наиля Вафиновна – ведущий научный сотрудник отдела проблем лабораторной диагностики туберкулеза и патоморфологии ГБУЗ «Московский научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы», кандидат медицинских наук
Адрес: 107014, Москва, ул. Стромынка, д. 10
Тел. + 7 (495) 603-30-33

Список литературы

1. Пальцев М.А. (ред) Кожная проба с препаратом «ДИАСКИНТЕСТ» – новые возможности идентификации туберкулезной инфекции. //
М.: ШИКО. – 2011. – 256 с.
2. Слогоцкая Л.В., Литвинов В.И., Филиппов А.В. и др. Чувствительность нового кожного теста «ДИАСКИНТЕСТ®» при туберкулезной инфекции
у детей и подростков. // Пробл. туберкулеза и болезней легких. – 2010. – № 1. – С. 10-15.
3. Слогоцкая Л.В., Сенчихина О.Ю., Никитина Г.В., Богородская Е.М. Эффективность кожного теста с аллергеном туберкулезным рекомбинантным
при выявлении туберкулеза у детей и подростков Москвы в 2013 г. // Педиатрическая фармакология. – 2015. – № 1. – С. 99-103.
4. Al-Orainey I. Diagnosis of latent tuberculosis: Can we do better? // Ann. Thorac. Med. – 2009. – Vol. 4. – N. 1. – P. 5-9.
5. Amicosante M., Ciccozzi M., Marcova R. Rational use of immunodiagnostic tools for tuberculosis infection: guidelines and cost effectiveness studies. //
New Microbiol. – 2010. – Vol. 33. – N. 2. – P. 93-107.
6. Antonucci G., Girardi E., Raviglione M.C., Ippolito G. Risk factors for tuberculosis in HIV-infected persons. A prospective cohort study. // JAMA. – 1995. –
Vol. 274. – N. 2. – P. 143-148.
7. Bamford A.R., Crook A.M., Clark J.E. et al. Comparison of interferon-gamma release assays and tuberculin skin test in predicting active tuberculosis (TB)
in children in the UK: a paediatric TB network study. // Arch. Dis. Child. – 2010. – Vol. 95. – N. 3. – P. 180–186.
8. Barry C., Boshoff H., Dartois V. et al. The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. // Nat. Rev. Microbiol. – 2009. –
Vol. 7. – N. 12. – P. 845–855.
9. Bendayan D., Hendler A., Litman K., Polansky V. The role of interferon-gamma release assays in the diagnosis of active tuberculosis. // Isr. Med. Assoc. J. –
2012. – Vol. 14. – N. 2. – P. 107–110.
10. Brock I., Weldingh K., Leyten E.M.R. et al. Specific T-cell epitopes for immunoassay-based diagnosis of Mycobacterium tuberculosis infection. //
J. Clin. Microbiol. – 2004. – Vol. 42. – N. 6. – P. 2379–2387.
11. Brouqui P., Delaique S., Parola P., Drancourt M. Interferon-gamma release assay: use and misuse. // Clin. Micriol. Infect. – 2012. – Vol. 18. – N. 11. –
P. 1053-1054.
12. Bua A., Molicotti P., Cannas S. et al. Tuberculin skin test and QuantiFERON in children. // New Microbiol. – 2013. – Vol. 36. – N. 2. – P. 153-156.
13. Burman W.J., Jones B.E. Clinical and radiographic features of HIV-related tuberculosis. // Semin. Respir. Infect. – 2003. – Vol. 18. – N. 4. – P. 263-271.
14. Catanzaro A., Daley C. A summary of the Third Global Interferon-γ Release Assay Symposium. // Infect. Control. Hosp. Epidemiol. – 2013. – Vol. 34. – N. 6. –
P. 619-624.
15. Cattamanchi A., Smith R., Steingart K. et al. Interferon-gamma release assays for the diagnosis of latent tuberculosis infection in HIV-infected individuals:
a systematic review and meta-analysis. // J. Acquir. Immune. Defic. Syndr. – 2011. – Vol. 56. – N. 3. – P. 230–238.
16. Chapman A., Munkanta M., Wilkinson K. et al. Rapid detection of active and latent tuberculosis infection in HIV-positive individuals by enumeration
of Mycobacterium tuberculosis-specific T cells. // AIDS. – 2002. – Vol. 16. – P. 2285-2293.
17. Cheallaigh C.N., Fitzgerald I., Grace J. et al. Interferon Gamma Release Assays for the diagnosis of latent tb infection in HIV-infected individuals in a low TB
burden country. // PloS One. – 2013. – Vol. 8. – N. 1. – e53330.
18. Chee C., Barkham T., Khinmar K. et al. Quantitative T-cell interferon-gamma responses to Mycobacterium tuberculosis-specific in active and latent
tuberculosis. // Eur. J. Clin. Microbiol. Infect. Dis. – 2009. – Vol. 28. – P. 667-670.
19. Chen J., Sun J., Zhang R. et al. T-SPOT.TB in the diagnosis of active tuberculosis among HIV-infected patients with advanced immunodeficiency. //
AIDS Res. Hum. Retroviruses. – 2011. – Vol. 27. – P. 289-294.
20. Chiappini E., Accetta G., Bonsiqnori F. et al. Interferon-γ release assays for the diagnosis of Mycobacterium tuberculosis infection in children: a systematic
review and meta-analysis. // Int. J. Immunopathol. Pharmacol. – 2012. – Vol. 25. – N. 3. – P. 557–564.
21. Clark S., Martin S., Pozniak A. et al. Tuberculosis antigen-specific immune responses can be detected using enzyme-linked immunospot technology
in human immunodeficiency virus (HIV)-1 patients with advanced disease. // Clin. Exp. Immunol. – 2007. – Vol. 150. – N. 2. – P. 238-244.
22. Connell T.G., Zar H.J., Nicol M.P. Advances in the diagnosis of pulmonary tuberculosis in HIV-infected and HIV-uninfected children. // J. Infect. Dis. – 2011. –
Vol. 204. – N. 4. – P. 1151–1158.
23. Cruz A.T., Starke J.R. Pediatric tuberculosis. // Pediatr. Rev. – 2010. – Vol. 31. – N. 1. – P. 13-25.
24. Detjen A., Keil T., Roll S. et al. Interferon-gamma release assays improve the diagnosis of tuberculosis and nontuberculous mycobacterial disease in children
in a country with a low incidence of tuberculosis. // Clin. Infect. Dis. – 2007. – Vol. 45. – P. 322-328.
25. Dheda K., Schwander S., Zhu B. et al. The immunology of tuberculosis: from bench to bedside. // Respirology. – 2010. – Vol. 15. – P. 433–450.
26. Diel R., Wrighton-Smith P., Zellweger J. Cost-effectiveness of interferon-gamma release assay testing for the treatment of latent tuberculosis. //
Eur. Respir. J. – 2007. – Vol. 30. – N. 2. – P. 321–332.
27. Diel R., Loddenkemper R., Meywald-Walter K. et al. Predictive value of a whole blood IFN-gamma assay for the development of active tuberculosis disease
after recent infection with Mycobacterium tuberculosis. // Am. J. Respir. Crit. Care Med. – 2008. – Vol. 177. – N. 10. – P. 1164–1170.

28. Diel R., Goletti D., Ferrara G. et al. Interferon-γ release assays in the diagnosis of latent M. tuberculosis infection: A systematic review and meta-analysis. //
Eur. Respir. J. – 2011. – Vol. 37. – N. 1. – P. 88-99.
29. Doyle J.S., Bissessor M., Denhold J.T. et al. Latent Tuberculosis screening using interferon-gamma release assays an Australian HIV-infected cohort: is routine
testing worthwhile? // J. Acquir. Immune. Defic. Syndr. – 2014. – Vol. 66. – N. 1. – P. 48-54.
30. European Centre for Disease Prevention and Control. Use of interferon-gamma release assays in support of TB diagnosis. Stockholm: ECDC; 2011.
31. Ewer K., Deeks J., Alvarez L. et al. Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school
tuberculosis outbreak. // Lancet. – 2003. – Vol. 361. – N. 9364. – P. 1168-1173.
32. Ferrara G., Losi M., D’Amico R. et al. Use in routine clinical practice of two commercial blood tests for diagnosis of infection with Mycobacterium tuberculosis:
a prospective study. // Lancet. – 2006. – Vol. 367. – P. 1328–1334.
33. Fujita A., Ajisawa A., Harada N. et al. Performance of a whole-blood Interferon-Gamma Release Assay with Mycobacterium RD1-specific antigens among
HIV-infected persons. // Clin. Dev. Immunol. – 2011. – Vol. 2011. – Article ID 325295.
34. Garcia G.F., Moura A.S., Ferreira C.S., Rocha M.O. Clinical and radiographic features of HIV-related pulmonary tuberculosis according to the level of immunosuppression. // Rev. Soc. Bras. Med. Trop. – 2007. – Vol. 40. – N. 6. – P. 622-626.
35. Ge L., Ma J.C., Han M. et al. Interferon-γ release assay for the diagnosis of latent Mycobacterium tuberculosis infection in children younger than 5 years:
a meta-analysis. // Clin. Pediatr. – 2014. – Vol. 53. – N. 13. – P. 1255-1263.
36. Getahun H., Harrington M., O`Brien R., Nunn P. Diagnosis of smear-negative pulmonary tuberculosis in people HIV infection or AIDS in resource-constrained
setting: informing urgent policy changes. // Lancet. – 2007. – Vol. 369. – N. 9578. – P. 2042-2049.
37. Glynn J.R., Murray J., Bester A. et al. Effect of duration of HIV infection and secondary tuberculosis transmission on tuberculosis incidence in the South African
gold mines. // AIDS. – 2008. – Vol. 22. – N. 14. – P. 1859-1867.
38. Grardon D., Erard V. Mycobacterium tuberculosis infection: signification, role and performance of measure of cell-mediated immune response. //
Rev. Med. Suisse. – 2014. – Vol. 10. – N. 425. – P. 816-819.
39. Haustein T., Ridout D., Hartley J. et al. The likelihood of an indeterminate test result from a whole-blood interferon-gamma release assay for the diagnosis
of Mycobacterium tuberculosis infection in children correlates with age and immune status. // Pediatr. Infect. Dis. J. – 2009. – Vol 28. – N. 8. – P. 669–673.
40. Janssens J., Roux-Lombard P., Perneger T. et al. Quantitative scoring of an interferon-gamma assay for differentiating active from latent tuberculosis. //
Eur. Respir. J. – 2007. – Vol. 30. – P. 722-728.
41. Kang Y., Lee H., Yoon H. et al. Discrepancy between the tuberculin skin test and the whole-blood interferon-gamma assay for the diagnosis of latent
tuberculosis infection in an intermediate tuberculosis burden country. // JAMA. – 2005. – Vol. 293. – N. 22. – P. 2756-2771.
42. Kanunfre K., Leite O., Lopes M. et al. Enhancement of diagnostic efficiency by a gamma interferon release assay for pulmonary tuberculosis. //
Clin.Vaccine Immunol. – 2008. – Vol. 15. – P. 1028-1030.
43. Kaplan J.E., Benson C., Holmes K.K. et al. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents:
recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. //
MMWR Recomm. Rep. – 2009. – Vol. 58 (RR-4). – P. 1-207.
44. Kunnath-Velayudhan S., Gennaro M. Immunodiagnosis of tuberculosis: a dynamic view of biomarker discovery. // Clin. Microbiol. Rev. – 2011. – Vol. 24. –
N. 4. – P. 792-805.
45. Lalvani A. Pathan A. Durkan H. et al. Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigenspecific T cells. // Lancet. – 2001. – Vol. 357. – P. 2017-2021.
46. Lalvani A. Diagnosis tuberculosis infection in the 21st century: new tools to tackle an old enemy. // Chest. – 2007. – Vol. 131. – N. 6. – P. 1898-1906.
47. Lalvani A., Pareek M. A 100 year update on diagnosis of tuberculosis infection. // Br. Med. Bull. – 2010. – Vol. 93. – P. 69-84.
48. Lange C., Pai M., Drobniewski F., Migliori G. Interferon-gamma release assay for the diagnosis of active tuberculosis: sensible or silly? // Eur. Respir. J. –
2009. – Vol. 33. – N. 6 – P. 1250-1253.
49. Latorre I., De Souza-Galvao M., Ruiz-Manzano J. et al. Quantitative evaluation of T-cell response after specific antigen stimulation in active and latent
tuberculosis infection in adults and children. // Diagn. Microbiol. Infect. Dis. – 2009. – Vol. 65. – N. 3. – P. 236-246.
50. Latorre I., Martinez-Lacasa X., Font R. et al. IFN-γ response on T-cells based assays in HIV-infected patients for detection of tuberculosis infection. //
BMC Infect. Dis. – 2010. – Vol. 10. – P. 348.
51. Lee J., Choi H., Park I. et al. Comparison of two commercial interferon-gamma assay for diagnosis Mycobacterium tuberculosis infection. // Eur. Respir. J. –
2006. – Vol. 28. – N. 1. – P. 24-30.
52. Lein A., von-Reyn C., Ravn P. et al. Cellular immune responses to ESAT-6 discriminate between patients with pulmonary disease due to Mycobacterium
tuberculosis. // Clin. Diagn. Lab. – 1999. – Vol. 6. – P. 606-609.
53. Lewinsohn D.A., Gennaro M.L., Scholvinck L., Lewinsohn D. M. tuberculosis immunology in children: diagnostic and therapeutic challenges and
opportunities. // Int. J. Tuberc. Lung. Dis. – 2004. – Vol. 8. – N. 5. – P. 658-674.
54. Liebeschuetz S., Bamber S., Ewer K. et al. Diagnosis of tuberculosis in South African children with a T-cell-based assay: a prospective cohort study. //
Lancet. – 2004. – Vol. 364. – P. 2196-2203.
55. Ling D., Pai M., Davids V. et al. Are interferon-γ release assays useful for diagnosing active tuberculosis in a high-burden setting? // Eur. Respir. J. – 2011. –
Vol. 38. – P. 649-656.
56. Ling D., Nicol M.P., Pai M. et al. Incremental value of T-SPOT.TB for diagnosis of active pulmonary tuberculosis in children in a high-burden setting:
a multivariable analysis. // Torax. – 2013. – Vol. 68. – N. 9. – P. 860–866.
57. Machingaidze S., Wiysonge C.S., Gonzalez-Angulo Y. et al. The utility of an interferon-gamma release assay for diagnosis of latent tuberculosis infection and
disease in children: a systematic review and meta-analysis. // Pediatr. Infect. Dis. J. – 2011. – Vol. 30. – N. 8. – P. 694-700.

89. Souza J.M., Evangelista M.S., Trajman A. Added value of QuantiFERON TB-gold in tube for detecting latent tuberculosis among persons living with HIV/AIDS. //
Biomed. Rec. Int. – 2014. – Vol. 2014. – Article ID 294963.
90. Starke J.R. New concepts in childhood tuberculosis. // Curr. Opin. Pediatr. – 2007. – Vol. 19. – N. 3. – P. 306-313.
91. Starke J.R. Interferon-γ release assays for diagnosis of tuberculosis infection and disease in children. // Pediatrics. – 2014. – Vol. 134. – N. 6. – P. 1763-1773.
92. Stephan C., Wolf T., Goetsch U. et al. Comparing QuantiFERON-tuberculosis gold, T-SPOT tuberculosis and tuberculin skin test in HIV-infected individuals
from a low prevalence tuberculosis country. // AIDS. – 2008. – Vol. 22. – N. 18. – P. 2471-2479.
93. Streeton J., Desem N., Jones S. Sensitivity and specificity of a gamma interferon blood test for tuberculosis infection. // Int. J. Tuberc. Lung Dis. – 1998. –
Vol. 2. – P. 443-450.
94. Sun L., Xiao J., Miao Q. et al. Interferon gamma release assay in diagnosis of pediatric tuberculosis: a meta-analysis. // FEMS Immunol. Med. Microbiol. –
2011. – Vol. 63. – N. 2. – P. 165–173.
95. Tan C.K., Hung C.C., Lai C.C. et al. Diagnosis of active tuberculosis by enzyme-linked immunospot assay for interferon-gamma in HIV-infected patients. //
J. Acquir. Immune Defic. Syndr. – 2010. – Vol. 53. – N. 4. – P. 546-547.
96. Wallis R., Pai M., Menzies D. et al. Biomarkers and diagnostics for tuberculosis: progress, needs, and translation into practice. // Lancet. – 2010. – Vol. 375. –
P. 1920–1937.
97. Walzl G., Ronacher K., Hanekom W. et al. Immunological biomarkers of tuberculosis. // Nat. Rev. Immunol. – 2011. – Vol. 11. – N. 5. – P. 343-354.
98. Wang S., Powell D., Nagaraja H. et al. Evaluation of a modified interferon-gamma release assay for the diagnosis of latent tuberculosis infection in adult and
paediatric populations that enables delayed processing. // Scand. J. Infect. Dis. – 2010. – Vol. 42. – N. 11-12. – P. 845-850.
99. Weinfurter P., Blumberg H.M., Goldbaum G. et al. Predictors of discordant tuberculin skin test and QuantiFERON®-TB Gold In-Tube results in various high-risk
groups. // Int. J. Tuberc. Lung Dis. – 2011. – Vol. 15. – N. 8. – P. 1056-1061.
100. WHO. World Health Organization website. Available: http://whqlibdoc.who.int/publications/2011/9789241564380_eng.pdf. Accessed 2011 September 22.
101. Winthrop K.L., Weinblatt M.E., Daley C.L. You can’t always get what you want, but if you try sometimes (with two tests – TST and IGRA – for tuberculosis)
you get what you need. //Ann. Rheum. Dis. – 2012. – Vol. 71. – N. 11. – P. 1757-1760.
102. Wrighton-Smith P., Zellweger J. Direct costs of three models for the screening of latent tuberculosis infection. // Eur. Respir. J. – 2006. – Vol. 28. – P. 45-50.
103. Yates F., Janakiraman A., Headly A. et al. Attitudes towards latent tuberculosis among physicians in training: the role of BCG vaccination. // J. Community.
Health. – 2015. – Vol. 40. – N. 2. – P.364-366.